Alpha-glutathione S-transferase and serum aminotransferases in Schistosomiasis mansoni patients with or without hepatitis C virus

ABSTRACT

The present study evaluated delta-Glutathione-S-transferase as a biochemical marker for hepatocellular damage in schistosomiasis mansoni patients, with or without chronic hepatitis C [HCV] patients as compared to controls. Alpha GST, ALT and AST were assayed in sera of GI 20 schistosomiasis mansoni patients with HCV, GII 16 schistosomiasis mansoni patients without HCV, GIII 19 pure HCV patients and GIV 20 normal controls. The results showed that delta-Glutathione-S-transf erase was less sensitive and less specific but more accurate than ALT and AST as a liver affection marker in HCV patients