AIDS-related sinonasal Burkitt lymphoma successfully treated with intensive chemotherapy regimen and high active antiretroviral therapy
Hematology, Oncology and Stem Cell Therapy. 2011; 4 (1): 41-44
Dans Anglais
| IMEMR
| ID: emr-110146
ABSTRACT
Burkitt lymphoma [BL] is the second most common AIDS-related lymphoma. Primary sinonasal BL in HIV patients is extremely rare and treatment data in this subset of patients is almost nonexistent. Recently, a few studies reported promising results treating HIV-associate BL with an intensive chemotherapy regimen. The use of highly active antiretroviral therapy [HAART] concomitantly with chemotherapy seems to improve patient outcomes, but this topic is still controversial due to potential drug interactions. We report a case of a 29-year old woman diagnosed with AIDS presenting with symptoms of chronic sinusitis. Subsequent investigation by CT scan and endoscopic biopsy discovered a sinonasal BL in an early stage. The patient was treated with intensive chemotherapy and HAART and achieved a complete remission and long-term immunologic recovery. This case report describes a rare entity whose natural history, treatment and prognosis is infrequently characterized in the medical literature
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Indice:
Méditerranée orientale
Sujet Principal:
Protocoles de polychimiothérapie antinéoplasique
/
Taux de survie
/
Résultat thérapeutique
/
Lymphome lié au SIDA
/
Thérapie antirétrovirale hautement active
Type d'étude:
Enquête cas-témoins / Études cas/témoins
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Hematol. Oncol. Stem Cell Ther.
Année:
2011
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