Promising early results for keloid treatment with intralesional colchicine: a clinical and histopathological study
New Egyptian Journal of Medicine [The]. 2009; 41 (4): 364-370
Dans Anglais
| IMEMR
| ID: emr-111495
ABSTRACT
To evaluate the effect ofcolchicine local infiltration in the treatment of keloids. Prospective study. National Hepatology and Tropical Medicine Research Institute [NHTMRI]. In a clinical trial, 14 cases with keloids were treated by local infiltration ofcolchicine. The results were evaluated objectively and subjectively. Lesional biopsy was obtained before and after treatment and examined by light microscopy. Marked reduction of the size of the lesions and decrease of such complaints as itching and erythema were noted. Favorable results were obtained according to the patients in 83.4% and according to the opinion of the medical examiner in 91.7% of cases. Systemic complications of colchicine absorption, i.e. nausea, did not occur in any patient. Histopathological examination of the lesions after colchicine infiltration reveled marked reduction in the density of collagen bundles, which are widely dispersed through out the dermis. intralesional infiltration of colchicine is safe and effective treatment, of keloids
Recherche sur Google
Indice:
Méditerranée orientale
Sujet Principal:
Injections intralésionnelles
/
Colchicine
/
Résultat thérapeutique
/
Chéloïde
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
New Egypt. J. Med.
Année:
2009
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS