[Comparison of non-HDL cholestrol level with LDL, cholesterol and other lipids markers level regarding investigation of lipoproteins disorder in hospitalizedpatients in Mazandran Heart Hospital]
Journal of Mazandaran University of Medical Sciences. 2009; 19 (71): 80-83
Dans Persan
| IMEMR
| ID: emr-111963
ABSTRACT
Considering some restrictions of serum low density lipoprotein [LDL] as a marker for Coronary Artery Disease [CAD] risk factor and also the importance of apo B as a signinificant risk factor for CAD, measurement of non-HDL cholesterol has great value as a risk factor for CAD. Non-HDL cholesterol [total cholesterol minus HDL cholesterol] contains all lipoproteins including apo-lipoproteins. In this study, 200 hospitalized patients [100 men and 100 women] with the diagnosis of CAD, documented by coronary angiography and 100 persons with normal angiography were recruited as case and control groups, respectively. Non-HDL cholesterol non-HDL-c was compared with LDL- cholesterol as a risk factor for CAD. Measured levels of triglyceride, total cholesterol, lipoprotein atherogenic a [Lpa] and non-HDL-c were significantly higher than those in control group. HDL level was lower in patients group. Correlation analysis showed that non-HDL-c [and not LDL cholesterol] had a higher reverse correlation triglyceride level. Measurement of non-HDL-c could be a good marker in atherogenic lipoproteins. Furthermore, due to potential power of its other atherogenic lipoproteins, it cannot be measured by LDL alone
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Indice:
Méditerranée orientale
Sujet Principal:
Apolipoprotéines B
/
Maladie des artères coronaires
/
Facteurs de risque
/
Lipoprotéines
/
Cholestérol HDL
/
Cholestérol LDL
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Persan
Texte intégral:
J. Mazandaran Univ. Med. Sci.
Année:
2009
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