Synthesis and antimicrobial activity of triazolopyrimidine and related heterocycles

ABSTRACT

Pyrimidine derivatives have attracted considerable interest in the recent years. Their derivatives have been known to display a wide range of pharmacological activities[1-8] such as antitumor, antioxidants, antiviral, antifungal and hepatoprotective activities. Prompted by these facts, and as a continuation of the previous work [9,10] on synthesis of biologically active heterocyclic compounds, we report in this investigation on the preparation of new series of biologically active pyrimidine derivatives