[ effect of aerobic training on the amount of GFR and excreted of creatinine in patients with chronic kidney]

ABSTRACT

The main characteristic of kidney disease is the decrease in Glomerular filtration Rate [GFR]. Physical exercise seems to influence GFR and the operation of kidney. The study has been conducted to determine the effect of eight weeks running on treadmills on the amount of GFR and another factor of operation of kidney of patients with chronic renal. Twenty seven subjects were chosen among male patients with chronic renal who had gone to kidney disease clinics. Before the beginning of the exercise period, blood test and 24 hour urine samples were taken and the amounts of the GFR were calculated using the Creatinine Clearance. An exercising program was given to the empirical group including eight weeks running on treadmills with the intensity of 50-80% maximal heart rate, which was practiced thrice a week, each session lasting 30-40 minutes. After the end of the exercising period, blood and urine tests were taken from both control and experimental groups under the same condition. Meaningful differences was perceived in the amount of GFR between control and empirical groups after 8 Week Running on Treadmills [P= 0.03]. There was also a significant difference between excreted creatinine of the 24 hour urine of the control group and empirical group after 8 Week Running on Treadmills [P= 0.003]. But there was no meaningful difference in the amount of creatinine serum [P= 0.8] and serum urea nitrogen [P= 0.1] between control and empirical groups after eight weeks running on treadmills. Aerobic activities could be prevent chronic renal in the first stages. It can also be effective in the prevention or postponement of the development of chronic renal failure