[Abu-Najma] Syndrome: exogenous steroid induced Cushing's with serious consequences. A report of two cases

ABSTRACT

We describe and report two cases of what we called Abu-Najma Syndrome, caused by the ingestion of 'Abu-Najma' tablets dexamethasone containing tablets promoted as [beauty tablets]. We believe the use of Abu-Najma is fast spreading among young ladies in Sudan. The syndrome has very serious consequences; a concerted effort is required to increase public awareness and prevent the problem. The commonest cause for Cushing's syndrome as well as secondary adrenal failure is the use of exogenous steroids. In this setting steroids are almost always prescribed for treatment of a medical condition. Side effects are usually discussed with the patients beforehand. However, self medication with steroids for non-medical reasons puts patients at increased risk of side effects. The use of steroid containing preparation either topical or oral for cosmetic reasons is on the increase. The following case histories illustrate the dangers associated with such a practice