Related factors for rectosigmoid hyperplastic polyps: a hospital-based study

ABSTRACT

Little evidence is available about the related factors for colorectal hyperplastic polyps in Taiwan. The aim of this study was to explore the prevalence of rectosigmoid hyperplastic polyps and to determine the related factors. Medical center in Taichung city, Taiwan Retrospective hospital-based, cross-sectional study. We analyzed the medical records of all subjects receiving periodic health examination at one medical center in Taichung city in Taiwan from 2001 to 2004. A total of 4413 subjects were enrolled in this study. All subjects underwent a 60-cm flexible sigmoidoscopic examination and laboratory survey. Prevalence of hyperplastic Polyps and related factors.There were 2444 men [55.4%] and 1969 women [44.6%]. The mean age was 49.3 years [standard deviation 12.3, range from 20 to 87]. The overall prevalence of hyperplastic polyps was 5.5%, with higher prevalence in men than in women [6.9% Vs 3.7%, p < 0.001]. After controlling for the other co-variates, multivariate logistic regression model showed that the related factors for hyperplastic polyps were increasing age [OR = 1.03, 95% CI = 1.02 -1.05, p < 0.001], male gender [OR =1.79, 95% CI = 1.31 - 2.46, p < 0.001], generalized obesity [OR = 1.59, 95% CI = 1.10 - 2.28, p = 0.012], and smoking [OR = 1.40, 95% CI = 1.02 - 1.93, p = 0.038]. These findings reveal that increasing age, male gender, generalized obesity and smoking are the related factors for rectosigmoid hyperplastic polyps