Congenital heart disease in infants of diabetic mother's echocardiographic study

ABSTRACT

Study of neonates born to Mothers with diabetes mellitus [including Gestational diabetes] to detect the spectrum of congenital heart disease [CHD] using non-invasive echocardiographic screening. Between October2007 and January 2010, a prospective study of68 infants of diabetic mothers [IDMs] at Al-thawra teaching Hospital in Albaida-libya was arranged. .Family and maternal history included, cardiovascular system examination and echocardiography were performed. Total of 68 IDMs examined, Echocardiographic findings were patent foramen oval [72%].PDA [53%], ventricular septal defect both muscular and membranous [10%], atrial septal defect [6%], and valvular pulmonary stenosis [<2%], peripheral pulmonary stenosis [6%] Hypertrophied interventricular septum was seen in 60% of cases. Tetrology of fallot [3%], Hypo plastic left heart syndrome one case [<2%], TGAnot seen in this group of study, other complex cardiac Topography account 1.5%, isolated coarctation of aorta<2%. Overall incidence of congenital heart disease was 25% [without PDA, PFO, septum hypertrophy, peripheral PS]. Maternal diabetes is a significant risk factor for CHD. Careful evaluation and early diagnosis of CHD in this high-risk group are highly recommended and there is a need for development of postnatal screening programs for CHD in this risk group in our population, also our policy of antenatal hyperglycemia control need to be reviewed