Disseminated mycobacterium tuberculosis in an infant with aids

ABSTRACT

Disseminated Mycobacterium tuberculosis with involvement of liver, spleen, and bone marrow is a nonspecific and rare complication in human immunodeficiency virus [HIV] infected infants. Here, we report a six month old girl with fever, recurrent infections, bilateral axilary lymphadenitis, hepatomegaly, huge splenomegaly, and failure to thrive. The infant and her mother had positive enzyme immunoassay [EIA] and Western blot. HIV DMA PCR test of the infant was positive with subtype A [A1] in genotyping. A positive bone marrow aspirate staining for acid fast bacilli and PCR test on culture revealed Mycobacterium tuberculosis