[ role of methyl prednisolon in facilitating and reducing the number of dilatation sessions esophageal in children with caustic burns]

ABSTRACT

To examine The benefit of high dose of high dose Methyl Prednisolon [1g/1,73m2/d] to facilitate and reduce the number of dilitation sessions in children with esophageal stenos caused by caustic burns. This Prospective study was carried out in Damascus Children hospital. 18 children with grade II and III esophageal caustic burns injuries were involved over a period of 2 years [1/6/2007-1/6/2009]. MP was given [1g/1,73m2/d] over 10 days]. These children had regular dilatation sessions once every 2-3 / weeks. This study involved 18 children with esophageal caustic injuries .The age was between [8m- 11y] and 50% were boys. Alkalines were the most cause 17[95%]. Only 2 children needed more sessions after the 2 year study, whilst in one of previous stdies [without the application of medical treatment],13 out of 26 children[50%] need dilation sessions beyond 2 year [p-value = 0,0043.]. Methyl Prednisolon has facilitated the dilatation and subsequently reduced the need for surgical intervention. [0,0146 = p-value].