Relationship of alloantibody detection with number of blood transfusions
Pakistan Journal of Pathology. 2012; 23 (1): 14-18
Dans Anglais
| IMEMR
| ID: emr-132971
ABSTRACT
To study the presence of the alloantibodies and their relationship with the number of transfusions. Two hundred subjects undergoing regular blood transfusions with at least 5 pints of blood within last six months were included in the study. Out of 200 patients, 140 [70%] were transfusion depended thalassaemics, 20 [10%] were haemophilics receiving multiple transfusions, 20 [10%] patients were of aplastic anaemia and 20 [10%] patients were with chronic renal failure undergoing haemodialysis. Antibodies were detected in 9/200 [4.5%] subjects. Ninety four patients received 5-50 transfusions, 2.13% developed alloantibodies. Sixty five patients received >50-100 blood transfusions, 6.15% developed alloantibodies. Forty one patients received >100 blood transfusions, 7.31% developed alloantobodies. Frequency of red cell alloantobodies in our transfusion dependent patient population is 4.5%. The risk of developing alloantobodies increased with increasing number of blood transfusion irrespective of underlying disorder.
Recherche sur Google
Indice:
Méditerranée orientale
Sujet Principal:
Transfusion sanguine
Limites du sujet:
Adolescent
/
Adulte
/
Enfant
/
Enfant d'âge préscolaire
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Pak. J. Pathol.
Année:
2012
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS