Influence of helicobacter phylori infection on gastric emptying in non-ulcerative dyspeptic patients

ABSTRACT

Non-ulcerative dyspepsia is common clinical problem. There are controversies regarding the role of helicobacter pylori infection on gastric emptying in non-ulcerative dyspeptic patients, thus, the present study was designed. Fifty patients with non-ulcerative dyspepsia referring to Endoscopy unit of Taleghani hospital were included. Initial data including demographic and clinical data were gathered. Four biopsy samples were taken during endoscopy to assess helicobacter pylori infection [rapid urease test, culture and direct observation]. Scintigraphy [solid phase] was used to detect gastric emptying disorders. The study population included 20 males and 30 females. Flatulence was the most common chief complaint. Other clinical manifestations were distention, abdominal pain, and fullness. Two-third of patients with abdominal pain had noted epigastric pain. Thirty-five [70%] patients had H. pylori infection and 23 [46%] had reduced gastric emptying. We have found no statistically significant difference in gastric emptying between infected and non-infected dyspeptic patients.Results revealed that helicobacter pylori has no effect on gastric emptying in non-ulcerative dyspeptic patients