potential role of ozone in treatment of carbon monoxide toxicity

ABSTRACT

Carbon monoxide is one of the most toxic and widely spread domestic poisons. The most important medical condition that requires administration of oxygen is carbon monoxide toxicity. The oxygen in carbon monoxide toxicity can be administered at the normal oxygen tension or at higher tension [hyperbaric oxygen]. Ozone is a triatomic molecule, consisting of three oxygen atoms. It has a number of medical uses. In this study, 10 heavy smokers were tested for the effect of ozone therapy on their arterial oxygen in blood and their medical condition regarding any associated symptoms. Medical symptoms such as headache, anxiety, drowsiness showed some improvement. Arterial oxygen tension [PaO[2]] showed statistically significant increase after 5 sessions of ozone therapy in comparison to before treatment level, while the increase was statistically not significant after 10 sessions in comparison to its level after 5 sessions. Regarding the effect of ozone therapy on the level of carboxyhemoglobin, it showed that there was statistically significant reduction in the CoHb level after 5 sessions in comparison with the resting level [before treatment] and also, there was highly statistically decrease in its level after 10 sessions in comparison to its level after 5 sessions. Regarding ozone therapy on the PaCO2, it showed statistically non significant decrease in PaCO2 after 5 sessions of treatment in comparison to its resting level