Cerebrospinal fluid rhinorrhea complicating conventional radiotherapy in a patient with pituitary adenoma

ABSTRACT

A 24-year-old man with a history of non-functional pituitary adenoma was treated with conventional radiotherapy. Two months following radiotherapy, the tumour size had significantly decreased, but early post radiotherapy rhinorrhea. This case highlights two predisposing factors of cerebrospinal fluid leak after radiotherapy of pituitary adenomas, i.e. skull base erosion and rapid significant tumour regression