Vitamin B[6]: Deficiency diseases and methods of analysis
Pakistan Journal of Pharmaceutical Sciences. 2013; 26 (5): 1057-1069
Dans Anglais
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| ID: emr-138431
ABSTRACT
Vitamin B[6] [pyridoxine] is closely associated with the functions of the nervous, immune and endocrine systems. It also participates in the metabolic processes of proteins, lipids and carbohydrates. Pyridoxine deficiency may result in neurological disorders including convulsions and epileptic encephalopathy and may lead to infant abnormalities. The Intravenous administration of pyridoxine to patients results in a dramatic cessation of seizures. A number of analytical methods were developed for the determination of pyridoxine in different dosage forms, food materials and biological fluids. These include UV spectrometric, spectrofluorimetric, mass spectrometric, thin-layer and highperformance liquid chromatographic, electrophoretic, electrochemical and enzymatic methods. Most of these methods are capable of determining pyridoxine in the presence of other vitamins and complex systems in micro g quantities. The development and applications of these methods in pharmaceutical and clinical analysis mostly during the last decade have been reviewed
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Indice:
Méditerranée orientale
Sujet Principal:
Pyridoxine
/
Marqueurs biologiques
/
Techniques de chimie analytique
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Pak. J. Pharm. Sci.
Année:
2013
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