Renal responses to halogenated anaesthetics

ABSTRACT

Creatinine, urea, sodium potassium, sugar and blood osmolality were determined in sixty patients under anaesthesia [halothane group 20 cases; enflurane group 20 cases and methoxyflurane 20 cases]. The significant results obtained were in halothane group, there were increase in excretion of creatinine; sodium and potassium in urine; blood urea and urine volume in the first postoperative period. In the group of enflurane, sodium and potassium excretion in urine in the first day were decreased. Blood urea increased at the operative and third postoperative days. With methoxyflurane, the excretion of creatinine in urine was much reduced at the third and seventh postoperative days. Serum sodium decreased, while blood urea increased in the day of operation