Stem cells therapy as a treatment for spinal cord injury

ABSTRACT

Stem cells therapy holds a great promise to treat several degenerative diseases and repair damaged tissues that are otherwise very difficult to treat by conventional therapies. In future, stem cells therapy will treat spinal cord injury [SCI] which is a major problem associated with demyelination of neurons caused by trauma resulting in cell death that is irreplaceable. Patients usually survive with spinal cord injury but this trauma remains uncure. After SCI, endogenous neuroprogenitor cells migrate towards the affected tissue but many messenger cascades suppress their proliferative activity. Different exogenous stem cells sources are another option to treat SCI patients. Although there is no permanent cure of SCI patients but due to excitable development in the field of stem cells transplantation, promises a hope for its cure in future. Due to intricacy of factors involved after SCI, there is a need for combinatorial therapies