Bendamustine-induced immune hemolytic anemia in a chronic lymphocytic leukemia patient: a case report and review of the literature
Hematology, Oncology and Stem Cell Therapy. 2014; 7 (4): 162-164
Dans Anglais
| IMEMR
| ID: emr-153851
ABSTRACT
Bendamustine is an alkylating agent approved for the treatment of chronic lymphocytic leukemia [CLL] and B-cell non-Hodgkin lymphoma. There are scant reports on bendamustine-induced immune hemolytic anemia occurring mainly in CLL patients. We report a case of immune hemolytic anemia that developed after exposure to bendamustine in a 70-year-old female with CLL who was previously exposed to fludarabine. Previous exposure to fludarabine is a common finding in the majority of reported cases of bendamustine drug-induced immune hemolytic anemia [DIIHA], including our case. Bendamustine should be suspected as the cause of any hemolytic anemia that develops while on this drug, especially in CLL patients treated previously with fludarabine
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Indice:
Méditerranée orientale
Sujet Principal:
Leucémie chronique lymphocytaire à cellules B
/
Maladie chronique
/
Anémie hémolytique
/
Anémie hémolytique auto-immune
/
Moutardes à l'azote
Type d'étude:
Enquête cas-témoins / Études cas/témoins
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Hematol. Oncol. Stem Cell Ther.
Année:
2014
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