[Comparison of the analgesic effect of nitroglycerin added to lidocaine and lidocaine alone in the intravenous regional anesthesia]

ABSTRACT

Intravenous regional anesthesia is easy to administer, reliable, and cost effective so it is notable for limb surgery. Slow onset, tourniquet pain, and minimal postoperative pain are this methods limitation. This study evaluate the effect of adding nitroglycerine to lidocaine on sensory and motor block onset time, tourniquet pain, first time of analgesic requirement and dose of opiate. In a randomized, double blinded, clinical trial thirty patients of 18 to 60 years old ASA class I,II undergoing upper limb surgery were randomly allocated into group A [3mg/kg lidocaine diluted with saline to total volume of 40ml] and group B [300 micro g nitroglycerine added to 3mg/kg lidocaine diluted with saline to total volume of 40ml]. Sensory and motor block onset time, tourniquet pain, first time of analgesic requirement, dose of opiate, hemodynamic changes and complications have been recorded and assessed. Sensory block onset time, motor block onset time, tourniquet pain and analgesic requirement were significantly lower in group B than group A. The first time of analgesic requirement was longer in group B than group A. No complication was seen in both groups. Addition of nitroglycerine to lidocaine to intravenous regional anesthesia can hastens the onset time of sensory and motor block and decreases tourniquet pain and opioid