In situ characterization of B-and T-lymphocytes in basal cell carcinoma of the head and neck region
EMHJ-Eastern Mediterranean Health Journal. 1997; 3 (1): 58-67
Dans Anglais
| IMEMR
| ID: emr-156450
ABSTRACT
Twenty cases of basal cell carcinoma [BCC] of the head and neck region were examined immunohistochemically for the detection of T- and Blymphocytes. The results showed that the dense lymphocytic infiltrate surrounding neoplastic cells of BCC consisted chiefly of T-lymphocytes. The lymphocytic infiltrate revealed in parts a pattern of a small lymphocytic follicle with peripherally situated T cells and central B cells. The predominance of Tlymphocytes in BCC suggests a local cell-mediated immune response. However, the presence of B-lymphocytes indicates a possible humoral immune reaction. T cells may be responsible for regulating the proliferation, and thus the growth, of malignant epithelial cells in BCC
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Indice:
Méditerranée orientale
Sujet Principal:
Immunohistochimie
/
Lymphocytes B
/
Carcinome basocellulaire
/
Lymphocytes T
/
Anticorps monoclonaux
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
East Mediterr Health J.
Année:
1997
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