Serum interleukins and urinary microglobulin in children with idiopathic nephrotic syndrome
EMHJ-Eastern Mediterranean Health Journal. 2005; 11 (5-6): 993-1002
Dans Anglais
| IMEMR
| ID: emr-156832
ABSTRACT
We studied 60 children affected with idiopathic nephrotic syndrome [INS] plus 20 age and sex matched controls. The children with INS were divided into 3 groups of 20 first presentation, remission and relapse. A complete blood picture and complete urinalysis were done. Serum interleukin [IL]-1beta, IL-6, tumour necrosis factor [TNF] and quantitative urinary beta-2-microglobulin [beta-2-m] excretion were estimated. IL-1beta and IL-6 were significantly higher in the study groups, the first presentation and relapse groups having the highest concentrations. Serum TNF concentration and urinary beta-2-m excretion were significantly higher in the first presentation and relapse groups. Serum IL-1beta, IL-6 and TNF concentrations were able to select positively [100%] the first presentation and relapse groups, while these plus urinary beta-2-m excretion selected negatively [100%] the control group
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Indice:
Méditerranée orientale
Sujet Principal:
Azote uréique sanguin
/
Études cas-témoins
/
Loi du khi-deux
/
Enfant d'âge préscolaire
/
Analyse de variance
/
Hôpitaux pédiatriques
Limites du sujet:
Enfant
/
Femelle
/
Humains
langue:
Anglais
Texte intégral:
East Mediterr Health J.
Année:
2005
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