Serum endostatin and vascular endothelial growth factor levels in patients with pre-eclampsia
EMHJ-Eastern Mediterranean Health Journal. 2006; 12 (1-2): 178-187
Dans Anglais
| IMEMR
| ID: emr-156867
ABSTRACT
We evaluated the prognostic value of serum endostatin and vascular endothelial growth factor [VEGF] for diagnosis of pre-eclampsia. We determined VEGF and endostatin levels in the sera of 20 healthy, non-pregnant women and 64 pregnant women 20 healthy, 20 with mild pre-eclampsia and 24 with severe pre-eclampsia. Serum levels of these factors in non-pregnant women were similar to those in healthy pregnant women. However, serum levels were significantly higher with mild or severe pre-eclampsia compared with normal pregnancies and significantly higher with severe rather than with mild pre-eclampsia. Elevated levels significantly increased risk more than severity of pre-eclampsia. VEGF and endostatin could be used to differentiate between pre-eclamptic and normal pregnancies and to discriminate mild pre-eclampsia from severe pre-eclampsia
Recherche sur Google
Indice:
Méditerranée orientale
Sujet Principal:
Pré-éclampsie
/
Grossesse
/
Facteurs de croissance endothéliale
/
Facteur de croissance endothéliale vasculaire de type A
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
East Mediterr Health J.
Année:
2006
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS