Diagnostic value of homocysteine, C-reactive protein and bilirubin for coronary artery disease
EMHJ-Eastern Mediterranean Health Journal. 2007; 13 (3): 522-535
Dans Anglais
| IMEMR
| ID: emr-157021
ABSTRACT
We evaluated 3 new markers for coronary artery disease [CAD] [bilirubin, total homocysteine [t-Hcy] and high-sensitivity C-reactive protein [hs-CRP]] in 319 patients with chest pains divided into 2 groups based on coronary angiography CAD group [n = 262] and non-CAD group [n = 57]. A control group consisted of 50 healthy subjects. t-Hcy had the highest diagnostic value for diagnosis of angiographically documented patients; bilirubin had the lowest. The sensitivities and specificities [based on ROC curves] of bilirubin, hs-CRP and t-Hcy were 70.9%, 50% and 76.8% respectively, and 40.4%, 80.7% and 70.2% respectively. We conclude that serum bilirubin levels cannot identify people at risk of CAD and t-Hcy and hs-CRP may be stronger markers
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Indice:
Méditerranée orientale
Sujet Principal:
Bilirubine
/
Maladie des artères coronaires
/
Protéine C-réactive
/
Indice de masse corporelle
/
Homocystéine
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
East Mediterr Health J.
Année:
2007
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