[Effect of resistance training on serum interleukin-18 and C-reactive protein in obese men]

ABSTRACT

Previous studies have reported inconsistent findings about the effect of endurance training on level of interleukin-18 [IL-18] and high-sensitivity C-reactive protein [hsCRP] in obese individuals. This study was performed to determine the effect of resistance training on serum level of IL-18 and hsCRP in obese men. In this clinical trial, eighteen obese men were randomly divided into training and control groups. After 12-hours fasting, height, weight, body mass index, body fat percent, serum level of IL-18 and hsCRP were assessed before and after training period. Resistance training protocol consisted of twelve weeks training, 3 sessions training per week, each session for 60 minutes. Mean +/- SD of IL-18 were 323.34 +/- 46.57 pg/ml and 239.43 +/- 53.75 pg/ml in training and control groups, respectively. Mean +/- SD of hsCRP was 3.83 +/- 3.65 microg/ml and 3.03 +/- 2.98 microg/ml in training and control groups, respectively. This difference was not significant. Performing resistance training for twelve weeks did not significantly reduce IL-18 and hsCRP in obese men