Williams-Beuren Syndrome: manifestation with attention deficit hyper activity disorder and voiding dysfunction with kidney anomalies;good response to Ritalin

ABSTRACT

Williams-Beuren syndrome is a rare neurodevelopmental disease, in which mental retardation is common with this submicroscopic chromosomal deletion genetically disease. We reported a boy with Williams-Beuren syndrome and highlighted the clinical characteristics and response to treatment with Ritaline of such an individual with ADHD and voiding dysfunction. The patient was a six year-old boy with typical presentation of WBS and some psychiatric problems referred because of hyperactivity symptom and attention deficit. Children with mental retardation and WBS have a comorbidity of psychiatric disorders and kidney anomalies. Williams-Beuren syndrome can present with hyperactivity and Ritalin can improve some symptoms and voiding dysfunction