Early complications of percutaneous kidney biopsy during hospital stay

ABSTRACT

To evaluate the early complications of percutaneous kidney biopsy during hospital stay. This prospective study was performed in the Deptt of Nephrology, Lady Reading Hospital, Peshawar from September 2002 to June 2006. All patients meeting the criteria and undergoing percutaneous kidney biopsy were included in the study. Kidney biopsies were performed by experienced operators under local anesthesia with ultrasound guidance using 18 guage needle and spring loaded gun. Baseline FBC, haematocrit, coagulation profile, blood urea, serum creatinine, urinalysis and ultrasound were done before biopsy. Check ultrasound, FBC, haematocrit, 24 hour urine collection were obtained next morning. Total number of biopsies done during this period was 650. There were 400 [64%] males and 250 [36%] females, mean age was 38.5 years. Adequate sample [>10 glomeruli] were obtained in 97% cases. Over all hemorrhagic complications were observed in 4% [n=26] patients. Post biopsy bleeding was higher in females n=16 [61%] than males n=10 [28%]. Gross haematuria requiring blood transfusion was observed in 9 patients [1.3%]. Post kidney biopsy [24 hour] decline in HCT<10% was seen in 505 patient [78%] and>10% in 145 patients [22%]. After the procedure, 630 patients [97%] were discharged next morning. Percutaneous kidney biopsy using 18 gauge needle and automated spring loaded gun is a safe technique with minimal complications and adequate tissue sampling