[Evaluation the bleeding in patients maintained on oral anticoagulant therapy without interruption of their treatment after use of tranexamic acid mouthwash]

ABSTRACT

Today many patients with some reasons need the use of anticoagulant drugs ,that interruption of this drugs may be dangerous. The purpose of this study was to evaluate the use of tranexamic acid 5% mouthwash to control hemostasis in patients therapeutically anticoagulant medication undergo dental extraction without interruption of medication. This study was a descriptive study and the data collection method was direct observation. A total of 55 patients undergone 167 dental extraction without interruption of oral anticoagulant medication, were required to rinse with 10 ml of a tranexamic acid 5% mouthwash 4 times a day for 7 days postoperatively. Dental extraction was carried out by two surgeon. Data were analyzed using SPSS statistical software and descriptive analyzed done. Of 55 patients treated, 1 presented with postoperative bleeding on the third day after operation [1/8%]. In this patient international normalized ratios was grossly elevated on the day of the bleeding [6.1]. This study supports the consensus that simple dental extraction in patients maintained on oral anticoagulant therapy with use tranexamic acid 5% mouthwash, can be performed without reduction or intruption dose of anticoagulant medication, and hemostas occurred well