[Histopathological changes of urinary bladder after colocystoplasty in dogs]

ABSTRACT

To evaluate necropsy and histopathological changes in urinary bladder after colocystoplasty. Experimental study. Five healthy mixed breed dogs, weighing between 10 - 20 kg. Partial cystectomy [almost 50 percent] with immediate augmentation colocystoplasty was performed. The augmented bladders after utanasia were studied on the basis of necropsy and histopathological findings on day 45 after operation. Adhesion between graft site and adjacent viscera was the most important finding after necropsy. Histopathological findings were different types of inflammations [hemorrhagic 40%, purulent 40% and fibrinous 20%] and extension of urothelium on mucosal layer of the colon in graft site [60%]. Reparative responses in serosal layer like chronic inflammation, granular and dense fibrotic tissue formation were seen in 60%, too. On the basis of this study, in spite of adhesion and bladder inflammation, colon is a suitable part for increasing bladder capacity in dogs because of good accessibility and lack of undue tension