T lymphocyte activation and expression of costimulatory molecules in filarial elephantiasis
Benha Medical Journal. 2007; 24 (1): 467-477
Dans Anglais
| IMEMR
| ID: emr-168558
ABSTRACT
This study was carried in 48 patients with positive blood films for W. bancrofti microfilaria and 12 cross matched healthy control persons. All the studied cases were submitted to flow cytometric analysis of peripheral blood mononuclear cells using monoclonal antibodies against CD3, CD4, CD8, CD28, HLA-DR. In this study, there was a significant decrease in CD3 and CD4 T lymphocytes but the changes in CD8 T cells and CD28 expression on CD8 T lymphocytes was insignificant while the activation marker HLA-DR expression on CD4 T lymphocytes was increased
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Indice:
Méditerranée orientale
Sujet Principal:
Filariose lymphatique
/
Lymphocytes T
/
Antigènes HLA-DR
/
Antigènes CD4
/
Antigènes CD8
/
Antigènes CD3
/
Antigène CD28
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Benha Med. J.
Année:
2007
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