[ association between central corneal thickness and retinal fiber layer thickness with refractive error]

ABSTRACT

The association between central corneal thickness and retinal fiber layer thickness with refractive error [emmetropic, myopic and hyperopic eyes]. 180 eyes [64 emmetropic eyes, 70 myopic eyes, 46 hyperopic eyes] in young subjects [18-35 years of age] were randomly selected. The participants in this study didn't have any ocular pathology or any previous surgical history. Pachymetry pattern of RTVUE OCT in central corneal thickness [CCT] and retinal nerve fiber layer [RNFL] thickness were measured. Mean CCT was 539.36 +/- 36.37 microns. Emmetropic eyes had thinner corneas [emmetropic eyes 536.14, myopic eyes 539.67, hyperopic eyes 543.28 microns]. Myopic subjects had thinner RNFL thickness [myopic eyes 114.21, emmetropic eyes 121.05, hyperopic eyes 120.45]. Univariate analysis revealed that CCT is positively correlated with RNFL in hyperopic and myopic eyes. Our findings demonstrate that RNFL may have positively correlated with CCT in hyperopic and myopic eyes. RNFL had inversely correlated with the amount of myopia and positively correlated with hyperopia. CCT was not significantly correlated with refractive error