Human bocavirus among viral causes of infantile gastroenteritis

ABSTRACT

Human bocavirus [HBoV] infection possibly plays a role in gastroenteritis because of the frequent manifestation of gastrointestinal symptoms. Detect human bocavirus [HBoV] and assess its prevelance among gastroenteritis associated viral agents in infants with gastroenteritis in Benha University Hospital. The study was carried out on 100 stool samples collected from 100 infants with acute gastroenteritis for detection of Rotavirus [RV], Norovirus [NoV] and Astrovirus [AstV] by multiplex reverse transciptase polymerase chain reaction and detection of Adenovirus[AdV] and HBoV by multiplex polymerase chain reaction. Viral agents were detected in 57 [57%] samples; 51 [51%] samples show mono-infection while 6 [6%] samples show co-infection. Rotavirus, Norovirus, Adenovirus and astrovirus were detected in 37%, 14%, 7.0%, and 3% of the study population, respectively; HBoV was detected in 2%. This percentage of HBoV suggests that it might play a minor role in gastroenteritis