Distribution frequency of hepatitis C virus genotypes in pateints attending liaquat university hospital Jamshoro/Hyderabad

ABSTRACT

To assess the frequency of different genotypes of Hepatitis C virus in patients attending Liaquat University Hospital [LUH] Jamshoro Sindh. This descriptive cross sectional study was carried out at Department of Medicine at Liaquat University hospital Jamshoro from June to December 2012. A total of 107 patients with Hepatitis C fulfilling the selection criteria and with informed consent were included in the study. Blood samples were taken from patients for HCV genotyping. A qualified pathologist performed HCV genotyping. Total 107 patients of Hepatitis C were selected by non probability consecutive sampling. Mean age was 36.58 +/- 10.5 years. Fifty six [52.3%] were male and fifty one [47.7%] were female. The commonest genotype was genotype 3 [72.9%] followed by genotype 2 [18.7%], genotype 1 [7.5%] and genotype 4 [0.9%]. The commonest HCV genotype 3 subtype was subtype a [73.8%] followed by subtype b [25.2%] and subtype c [0.9%]. HCV genotype 3 with distribution frequency of 72.9% and subtype a with distribution frequency of 73.8% were the commonest in our study population.