Assessment of serum level of 25-hydroxyvitamin D in Iranian children with atopic dermatitis, in Kerman city, an area with high sun exposure

ABSTRACT

To determine the association between the severity of AD and serum level of 25[OH] vitamin D in Kerman, a desert area in southeast of Iran, that was performed for the first time in Iran. In this cross-sectional study 57 AD subjects and 19 healthy children under the age of 18 years old were enrolled. The serum levels of 25[OH] vitamin D were measured in the both groups. The severity of AD was evaluated according to SCORAD. According to our study, there was a significant association between serum level of vitamin D and severity of AD especially in moderate and severe forms of AD [p<0.001]. Our study revealed vitamin D deficiency in AD patients, thus, it is recommended to take vitamin D supplementation in AD patient. Additional research is needed in order to evaluate dysfunction of vitamin D receptor in AD patients