Report of a rare case of mucormycosis in association with plasma cell granuloma of the lung

ABSTRACT

In this article a rare case of mucormycosis and plasma cell granuloma in a diabetic female is presented. Mucormycosis is a rare fungal infection almost always limited to diabetic and immunocompromised hosts. It preferentially localizes in the nose [from which it may spread to the sinuses and brain], lungs, and gastrointestinal tract. The term plasma cell granuloma is used in preference to histiocytoma of the lung which was previously used to describe these lung tumors. They are now usually regarded as post-inflammatory granulomas. Control of the underlying diabetes mellitus, pulmonary lobectomy and intravenous amphotericin B administration following surgery comprised our therapeutic measures. Despite several reports regarding the poor prognosis following appropriate management, it is our belief that such a therapeutic plan is beneficial and effective. From the pathologic point of view it is interesting to have these two entities [mucormycosis and plasma cell granuloma] in association with each other