Prolongation of QTc duration and increased heart rate in patients with cirrhosis of liver
APMC-Annals of Punjab Medical College. 2012; 6 (1): 28-31
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Objective: To compare QTc duration and increasedheart rate in patients with cirrhosis with noncirrhoticcontrols
Design: Cross-sectionalanalytical study
Place and Duration of Study:Medical Unit 1 Allied Hospital Faisalabad between1st March 2011 to 30th August 2011
Patients andMethods: 50 patients of cirrhosis were selected inGroup-I. An equal number of non-cirrhotic patientswere taken as control and were included in Group-II. ECG was recorded and Heart rate[HR] and QTcinterval was calculated in both the groups.Comparison of increased prolongation of QTc andHeart Rate were done using independent samples ttest with significance level at 0.05
Results: Fiftypatients of cirrhosis of liver were inducted in Group-I with same number of non-cirrhotic patients ascontrol in Group-II. The mean +/- SD of QTc ofGroup-I was 0.472 +/- 0.012 sec and that in Group-IIwas 0.434 +/- 0.014 sec and that for HR in Group-Iand II were 79.26 +/- 10.08 and 74.24 +/- 7.58beats/min respectively. The mean QTc and HRvalues were significantly more in Group-I ascompared to Group-II with p value = 0.0001
Conclusion: Means of both HR and QTc weresignificantly higher in cirrhotic patients as comparedwith non-cirrhotic controls
Design: Cross-sectionalanalytical study
Place and Duration of Study:Medical Unit 1 Allied Hospital Faisalabad between1st March 2011 to 30th August 2011
Patients andMethods: 50 patients of cirrhosis were selected inGroup-I. An equal number of non-cirrhotic patientswere taken as control and were included in Group-II. ECG was recorded and Heart rate[HR] and QTcinterval was calculated in both the groups.Comparison of increased prolongation of QTc andHeart Rate were done using independent samples ttest with significance level at 0.05
Results: Fiftypatients of cirrhosis of liver were inducted in Group-I with same number of non-cirrhotic patients ascontrol in Group-II. The mean +/- SD of QTc ofGroup-I was 0.472 +/- 0.012 sec and that in Group-IIwas 0.434 +/- 0.014 sec and that for HR in Group-Iand II were 79.26 +/- 10.08 and 74.24 +/- 7.58beats/min respectively. The mean QTc and HRvalues were significantly more in Group-I ascompared to Group-II with p value = 0.0001
Conclusion: Means of both HR and QTc weresignificantly higher in cirrhotic patients as comparedwith non-cirrhotic controls
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Indice:
IMEMR
langue:
En
Texte intégral:
Ann. Punjab Med. Coll.
Année:
2012