EJMM-Egyptian Journal of Medical Microbiology [The]. 2015; 24 (4): 35-40
Dans Anglais
| IMEMR
| ID: emr-175720
ABSTRACT
Background:
Helicobacter pylori [H. pylori] expressed outer membrane proteins [OMP[s]] that assist in bacterial adherence to the gastric epithelium promoting successful colonization. One of these OMPs is the blood group antigen binding adhesin A [BabA] which bind to the fucosylated Lewis[b] blood group antigen [Le[b]] on the surface of gastric epithelial cells. Another OMP[s] is the sialic acid binding adhesin [SabA] that mediates H. pylori binding the specific sialyl dimeric Lewis[x] glycosphingolipid [Le[x]] on the gastric epithelium. A lot of discrepancies about the correlation between the presence of both babA and sabA genes and the apparent clinical outcome of H. pylori infection were reported
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Indice:
Méditerranée orientale
Sujet Principal:
Acides sialiques
/
Tumeurs de l'estomac
/
Protéines de la membrane externe bactérienne
/
Helicobacter pylori
/
Adhésines bactériennes
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Egypt. J. Med. Microbiol.
Année:
2015
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