[Molecular investigation of Y chromosome microdeletions in AZF regions of the non-obstructive azoospermic and oligospermic patients referred to Montaseriyeh infertility center in Mashhad]

ABSTRACT

Background and Aim: The Y-chromosome azoospermic factor [AZF] regions consist of genes whose specific roles and functions in spermatogenesis and fertility have not been completely clarified. Hence, recognition of the association between AZF microdeletions and male infertility has suggestions for the diagnosis, treatment, and genetic counseling. The main objective of the present study was investigation of Y chromosome microdeletions in the non-obstructive azoospermic and oligospermic patients in Mashhad and identification of appropriate STS markers associated with azoospermia and oligospermia