Predictive ability of [18]F-fluorodeoxyglucose positron emission tomography/computed tomography for pathological complete response and prognosis after neoadjuvant chemotherapy in triple-negative breast cancer patients

ABSTRACT

Objective The mortality of patients with locally advanced triple-negative breast cancer [TNBC] is high, and pathological complete response [pCR] to neoadjuvant chemotherapy [NAC] is associated with improved prognosis. This retrospective study was designed and powered to investigate the ability of [18]F-fluorodeoxyglucose positron emission tomography/computed tomography [[18]F-FDG-PET/CT] to predict pathological response to NAC and prognosis after NAC