Value of dedicated head and neck [18]F-FDG PET/CT protocol in detecting recurrent and metastatic lesions in post-surgical differentiated thyroid carcinoma patients with high serum thyroglobulin level and negative [131]I whole-body scan

ABSTRACT

Objective[s] In clinical practice, approximately 10-25% of post-surgical differentiated thyroid carcinoma [DTC] patients with high serum thyroglobulin [Tg] and negative [131]I whole-body scan [WBS] have poor prognosis due to recurrent or metastatic lesions after radioactive iodine treatment. The purpose of this study was to evaluate the value of [18]F-FDG PET/CT scan in DTC patients with high serum Tg level and negative [131]I WBS