Waterborn outbreak of vibrio cholera O1 ogawa; in wadh area of balochistan

ABSTRACT

To isolate the etiological agent of severe diarrheal outbreak, identification, antibiogram of isolated agent and preventive measures to control the spread of infection. Samples of stool and drinking water supply of affected area collected in Cary- Blair transport medium, inoculated on various media. The isolated strains were identified as responsible for diarrheal outbreak tested against antibiotics. The strain and antibiogram was further confirmed by Agha Khan University Hospital Laboratory in Karachi. Bolan Medical College Hospital, Quetta. Isolation of Vibrio cholerae O1, Ogawa, El Tor, antibiogram against isolated strain, and control of spread of infection. The etiological agent responsible for severe diarrheal disease outbreak was Vibrio cholerae O1, Ogawa El Tor. in which 148 persons affected including all ages and both sexes. Four deaths [2.7%] reported out of these affected patients. The isolated strain was same in all patients and water source. Susceptibility to antimicrobial drugs was determined showing sensitivity to Ampicillin, Choloramphenicol, Ofloxacin, Tetracycline, Nalidixic Acid , Gentamycin and resistance to Polymaxin B, and Cotrimaxazole. The drinking source of water was a shallow well which was sealed and alternative arrangements of drinking water were made from another source. Vibrio cholerae O1, Ogawa El Tor, strains were isolated as etiological agent for severe diarrheal disease outbreak, which was spread through drinking water. The source of drinking water was contaminated due to rain in this area. The isolated strain was most common pathogen in this area for severe diarrheal disease outbreaks, and mostly it spreads through contamination of water source. The strategy applied for prevention of disease was successful and no further case was reported