Serum miRNA-1 as a novel biomarker for acute myocardial infarction and unstable angina

ABSTRACT

Background: Coronary artery diseases are the predominant cause of morbidity and mortality in developed and developing countries. Thus, extraordinary efforts have been directed to determine the molecular and pathological characteristics of the diseased heart in order to develop novel diagnostic and therapeutic strategies miRNAs are class of abundant, non-coding RNAs that attracted scientists' attention for their promising role as diagnostic and prognostic biomarkers in cardiovascular diseases