Sequence analysis of the VSXI and SODl genes in families with Keratoconus and a review of the literature

ABSTRACT

Objective: Keratoconus [KC] is a non-inflammatory disorder of the cornea in which the cornea becomes thin and conical, inducing myopia and irregular astigmatism and resulting in mild to marked impairment of vision. The present study was designed to screen two candidate KC genes to identify pathogenic sequence variants responsible for KC in Saudi families