Repressing of SOX6 and SOX9 in situ chondrogenic differentiation of rat bone marrow stromal cells

Mohammad Hassan, Karimfar; Aliasghar, Peyvandi; Mohsen, Noorozian; Navid Ahmadi, Roozbahani; Reza Mastery, Farahani; Maryam Sadat, Khoramgah; Hadi, Azimi; Ayad, Bahadori; Hojjat Allah, Abbaszadeh

Mohammad Hassan, Karimfar; Aliasghar, Peyvandi; Mohsen, Noorozian; Navid Ahmadi, Roozbahani; Reza Mastery, Farahani; Maryam Sadat, Khoramgah; Hadi, Azimi; Ayad, Bahadori; Hojjat Allah, Abbaszadeh.

Anatomical Sciences Journal. 2015; 12 (2): 75-82

Dans Anglais | IMEMR | ID: emr-179354

ABSTRACT

ABSTRACT

Introduction:

SOX9 is a transcriptional activator which is necessary for chondrogenesis. SOX6 are closely related to DNA-binding proteins that critically enhance its function. Therefore, to carry out the growth plate chondrocyte differentiation program, SOX9 and SOX6 collaborate genomewide. Chondrocyte differentiation is also known to be promoted by glucocorticoids through unknown molecular mechanisms

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Indice: Méditerranée orientale langue: Anglais Texte intégral: Anat. Sci. J. Année: 2015

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Indice: Méditerranée orientale langue: Anglais Texte intégral: Anat. Sci. J. Année: 2015