Recombinant activated factor VII: a savior in management of postpartum hemorrhage

ABSTRACT

Bleeding, a major cause of morbidity and mortality, is one of the most difficult challenges for obstetricians and anesthesiologists. The management of major obstetric hemorrhage is challenging resulting in surgical and medical interventions, sometimes requiring hysterectomy. Use of Recombinant activated factor VII r[FVIIa] is a recent advancement in the control of PPH. In situations of intractable PPH, where primary measures to control hemorrhage fail, administration of rFVIIa should be considered before decision to perform a hysterectomy is undertaken. We hereby present a case report of a 21 year female presenting with post caesarean PPH refractory to standard therapy, managed successfully by r[FVIIa]