Could the mosaic pattern of chromosomal abnormality predict overall survival of patients with myelodysplastic syndrome?

ABSTRACT

Objective/background: Myelodysplastic syndromes [MDSs] are a group of monoclonal hematopoietic diseases consisting of a number of various entities. The presence of differences in chromosomal content of cells within the same individual is known as chromosomal mosaicism. The impact of mosaic pattern on the prognosis of MDS has been unclear. In this study, we aimed to determine the impact of mosaic pattern on the survival of patients with MDS