Frequency of Y chromosome microdeletions among Iranian infertile men with azoospermia and severe oligozoospermia: a meta-analysis

ABSTRACT

Background: While multiple factors can contribute to male infertility, genetic factors, such as chromosomal disorders or Y-chromosome microdeletion, are responsible for about 10% of male infertility. Considering the role of Y-chromosome microdeletions in men with oligozoospermia who volunteer for in vitro fertilization [IVF], the prevalence of such microdeletions in each particular community needs to be exactly determined. Hence, the present study attempted to analyze the available literature on the frequency of chromosome microdeletion among Iranian infertile men