Development of a high-resolution melting analysis method for CYP2C19*17 genotyping in healthy volunteers
AJMB-Avicenna Journal of Medical Biotechnology. 2016; 8 (4): 193-199
Dans Anglais
| IMEMR
| ID: emr-185095
ABSTRACT
Background:
Genetic polymorphisms of drug metabolisms by cytochrome P450 [P450s] could affect drug response, attracting particular interest in the pharmacogenetics. Due to the importance of CYP2C19* 17 allele and its capability of super- fast metabolism and also lack of information about distribution of the alleles in Iranian population, this research aimed to use High Resolution Melting [HRM] method compared to PCR-RFLP for genotyping healthy Iranian population
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Indice:
Méditerranée orientale
langue:
Anglais
Texte intégral:
Avicenna J. Med. Biotechnol.
Année:
2016
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