Methylation status of H19/IGF2 differentially methylated region in in vitro human blastocysts donated by healthy couples
IBJ-Iranian Biomedical Journal. 2017; 21 (1): 16-23
Dans Anglais
| IMEMR
| ID: emr-185663
ABSTRACT
Backgrund Imprinted genes are a unique subset of few genes, which have been differentially methylated region [DMR] in a parental origin-dependent manner during gametogenesis, and these genes are highly protected during pre-implantation epigenetic reprogramming. Several studies have shown that the particular vulnerability of imprinting genes during suboptimal pre- and peri-conception micro-environments often is occurred by assisted reproduction techniques [ART]. This study investigated the methylation status of H19/IGF2 DMR at high-quality expanding/expanded human blastocysts donated by healthy individuals to evaluate the risks linked to ART
Recherche sur Google
Indice:
Méditerranée orientale
Sujet Principal:
Blastocyste
/
Techniques in vitro
/
Empreinte génomique
/
Ilots CpG
/
Techniques de reproduction assistée
/
Épigenèse génétique
/
Iran
Limites du sujet:
Animaux
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Iran. Biomed. J.
Année:
2017
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS