Comparative in vitro evaluation of human dental pulp and follicle stem cell commitment

ABSTRACT

Objective: Pulp and periodontal tissues are well-known sources of mesenchymal stem cells [MSCs] that provide a promising place in tissue engineering and regenerative medicine. The molecular mechanisms underlying commitment and differentiation of dental stem cells that originate from different dental tissues are not fully understood. In this study, we have compared the expression levels of pluripotency factors along with immunological and developmentally-related markers in the culture of human dental pulp stem cells [hDPSCs], human dental follicle stem cells [hDFSCs], and human embryonic stem cells [hESCs]